My doctor gave me Celexa for chronic debilitating pain. I haven't tried it yet because I found out it is an anti-depressant and I am an active person who doesn't need this. However, I am beyond desperation with my pain. Is 10 mg. of Celexa a viable treatment for chronic pain? - Scarlette

A lot of people wonder, "If I am not a depressed person, is it worth the risk in side effects to take an anti-depressant for pain?" It is not unusual for one drug to have more than one use. Aspirin is an example of a versatile drug used to treat headaches, reduce fevers, prevent heart attacks, and calm inflammation. Even if you don't suffer from headaches, you might try aspirin if you are at risk for a heart attack.

Similarly, there have been several studies showing that certain medications used to fight depression are also effective in the treatment of chronic pain. In fact, antidepressants are over 74% more effective than placebo (sugar pill) in chronic pain studies. It is now common practice to try these medications to relieve pain.

Unfortunately, any drug might cause side effects and you are wise to consider that possibility. Common side effects of the serotonin-boosting antidepressants such as Celexa may include nausea, drowsiness or restlessness, and sexual dysfunction. These side effects can occur even if you are taking the medication for pain rather than depression.

As with most medications, you might experience no side effects at all, mild side effects, or side effects that you find to be intolerable. There is no way to predict which ones you may experience-if any. Once your doctor has determined that an antidepressant would be safe and possibly helpful, the next step is up to you.

If you decide to take the medication, it doesn't have to be forever. Give it time to work, then re-evaluate. Do you feel better overall? Always arrange a follow-up visit to determine whether a medication should be continued, adjusted, or stopped.

Amy Fogelstrom Chai, MD, MS, is an Internal Medicine Specialist with additional training in the area of medical research methods. Her experiences as a patient helped to redirect her priorities to home life and Christian ministry.